Recent Publications

Common carotid arteries of apoE-/-, PAI-1+/+ mice (A, C) and apoE-/-, PAI-1-/- mice (B, D) 8 weeks after ferric chloride injury. Microscopic sections were stained for elastin; magnification x200.
- Nagashima M, Yin ZF, Zhao L, White K, Zhu Y, Lasky N, Broze GJ, Fay WP, Morser J: Thrombin-activatable fibrinolysis inhibitor (TAFI) deficiency is compatible with murine life. J. Clin. Invest. 2002;109:101-110.
- Peng L, Bhatia N, Parker AC, Zhu Y, Fay WP: Endogenous vitronectin and plasminogen activator inhibitor-1 promote neointima formation in murine carotid arteries. Arterioscler Thromb Vasc Biol. 2002;22:934-939.
- Chuang S, Mehta R, and Fay WP: Prolonged low-dose thrombolytic therapy: A novel adjunctive strategy in the management of an infected right atrial thrombus. Clin. Cardiol. 2002;25:346-349.
- Zhu Y, Tomasiak R, Fay WP: Do Clinically-Relevant Circulating Concentrations of Radiographic Contrast Agents Inhibit Platelet-Dependent Arterial Thrombosis? Thromb. Res. 2002;105:413-418.
- Day SM, Duquaine D, Mundada LV, Menon RG, Khan BV, Rajagopalan S, Fay WP: Chronic iron administration increases vascular oxidative stress and accelerates arterial thrombosis. Circulation 2003; 107:2601-2606.
- Mundada LV, Prorok M, DeFord ME, Figuera M, Castellino FJ, Fay WP: Structure-function analysis of the streptokinase amino terminus (residues 1-59). J Biol Chem 2003; 278:24421-24427.
- Danenberg HD, Szalai, AJ, Swaminathan RV, Peng L, Chen Z, Seifert MS, Fay WP, Simon DI, Edelman ER: Increased thrombosis after arterial injury in human C-reactive protein-transgenic mice. Circulation 2003;108:512-515.
- Khil J, Im M, Heath A, Ringdahl U, Mundada L, Engleberg NC, Fay WP: Plasminogen enhances group A streptococcal virulence by streptokinase-dependent and streptokinase-independent mechanisms. J Inf Dis 2003; 188: 495-505.
- Peng L, Mundada L, Stomel JM, Liu JJ, Sun J, Yet S-F, Fay WP: Induction of heme oxygenase-1 expression inhibits platelet-dependent thrombosis. Antiox Redox Signal. 2004;6:729-735.
- Sun H, Ringdahl U, Homeister J, Fay WP, Engleberg C, Yang A, Wang X, Sjobring U, Ginsburg D: Plasminogen is a critical host pathogenicity factor for group A streptococcal infection. Science 2004;305:1283-1286.
- Rusconi CP, Roberts JD, Pitoc GA, Nimjee SM, White RR, Quick G, Fay WP, Sullenger BA: Antidote-mediated control of anticoagulant aptamer activity in vivo. Nature Biotechnology 2004;22:1423-1428.
- Parker AC, Mundada LV, Schmaier AH, Fay WP: Factor VLeiden inhibits fibrinolysis in vivo. Circulation 2004;110:3594-3598.
- Day SM, Reeve JL, Pedersen, B, Farris DM, Myers DD, Im M, Wakefield TW, Mackman N, Fay WP: Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall. Blood 2005;105:192-198.